APA
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Chen, W., Wang, X., Sun, J., Wang, X., Zhu, Z., Ayhan, D. H., … Guo, L. (2024). Two telomere-to-telomere gapless genomes reveal insights into Capsicum evolution and capsaicinoid biosynthesis. Nature Communications.
Chicago/Turabian
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Chen, Weikai, Xiangfeng Wang, Jie Sun, Xinrui Wang, Zhangsheng Zhu, Dilay Hazal Ayhan, Shu Yi, et al. “Two Telomere-to-Telomere Gapless Genomes Reveal Insights into Capsicum Evolution and Capsaicinoid Biosynthesis.” Nature Communications (2024).
MLA
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Chen, Weikai, et al. “Two Telomere-to-Telomere Gapless Genomes Reveal Insights into Capsicum Evolution and Capsaicinoid Biosynthesis.” Nature Communications, 2024.
BibTeX Click to copy
@article{weikai2024a,
title = {Two telomere-to-telomere gapless genomes reveal insights into Capsicum evolution and capsaicinoid biosynthesis},
year = {2024},
journal = {Nature Communications},
author = {Chen, Weikai and Wang, Xiangfeng and Sun, Jie and Wang, Xinrui and Zhu, Zhangsheng and Ayhan, Dilay Hazal and Yi, Shu and Yan, Ming and Zhang, Lili and Meng, Tan and Mu, Yu and Li, Jun and Meng, Dian and Bian, Jianxin and Wang, Ke and Wang, Lu and Chen, Shaoyin and Chen, Ruidong and Jin, Jingyun and Li, Bosheng and Zhang, Xingping and Deng, Xing Wang and He, Hang and Guo, Li}
}
Chili pepper (Capsicum) is known for its unique fruit pungency due to the presence of capsaicinoids. The evolutionary history of capsaicinoid biosynthesis and the mechanism of their tissue specificity remain obscure due to the lack of high-quality Capsicum genomes. Here, we report two telomere-to-telomere (T2T) gap-free genomes of C. annuum and its wild nonpungent relative C. rhomboideum to investigate the evolution of fruit pungency in chili peppers. We precisely delineate Capsicum centromeres, which lack high-copy tandem repeats but are extensively invaded by CRM retrotransposons. Through phylogenomic analyses, we estimate the evolutionary timing of capsaicinoid biosynthesis. We reveal disrupted coding and regulatory regions of key biosynthesis genes in nonpungent species. We also find conserved placenta-specific accessible chromatin regions, which likely allow for tissue-specific biosynthetic gene coregulation and capsaicinoid accumulation. These T2T genomic resources will accelerate chili pepper genetic improvement and help to understand Capsicum genome evolution. Chili pepper (Capsicum) is an important vegetables known for fruit pungency given by capsaicinoids. Here, the authors assemble the telomere-to-telomere genomes of a pungent pepper C. annuum and its non-pungent wild relative C. rhomboideum and reveal insights into Capsicum evolution and capsaicinoid biosynthesis.